What causes muscle fibre necrosis in necrotizing myopathy? The authors of a new study propose that specific autoantibodies contribute to disease via immune-mediated processes; but given that these processes also occur in muscular dystrophies, how likely is that these antibodies trigger muscle fibre necrosis?
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Dalakas, M. Are autoantibodies pathogenic in necrotizing myopathy?. Nat Rev Rheumatol 14, 251–252 (2018). https://doi.org/10.1038/nrrheum.2018.54
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DOI: https://doi.org/10.1038/nrrheum.2018.54