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A plethora of pleiotropy across complex traits

Nature Genetics volume 48, pages 707–708 (2016)Cite this article

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A new analysis has identified hundreds of loci that are associated with multiple traits or diseases by comparing genome-wide association study (GWAS) data for 42 complex traits. The study uses the power of GWAS to provide evidence of pairs of traits with a likely causal relationship.

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Figure 1: Inferring causal relationship between traits based on asymmetry in GWAS results.

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Authors and Affiliations

  1. Peter M. Visscher and Jian Yang are at the Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.,

    Peter M Visscher & Jian Yang

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  1. Peter M Visscher
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  2. Jian Yang
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Correspondence to Peter M Visscher or Jian Yang.

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The authors declare no competing financial interests.

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Visscher, P., Yang, J. A plethora of pleiotropy across complex traits. Nat Genet 48, 707–708 (2016). https://doi.org/10.1038/ng.3604

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